ABSTRACT
Objective To discuss the correlation of the left coronary artery morphology and occurrence of acute myocardial infarction (AMI) with left main lesion and in-hospital mortality.Methods This was a retrospective study of clinical information and angiographic data of 176 patients admitted from January 2010 to April 2015 with left main lesion in the First Affiliated Hospital of Harbin Medical University.The patients were divided into left main acute myocardial infarction group and left main non-acute myocardial infarction group,and then the left main AMI group was further divided into the survival group and the deceased group according to the situation of in-hospital death.QCA software was used to measure the anatomical morphology of left coronary artery.The anatomical morphology of left coronary artery between the two groups was compared,and univariate analysis and logistic regression analysis were applied to analyze the factors of AMI occurrence and in-hospital mortality in AMI patients with left main lesion.Results The angle between the left anterior descending artery (LAD) and the left circumflex artery (LCX) of the LM-AMI group was smaller than the non-acute myocardial infarction group (P＜0.05),but there was no significant difference in the diameter and length of left main coronary artery (LM),the diameter of LAD and LCX,the angle between LM and LAD and the angle between LM and LCX between the two groups (P＞0.05).The risk of LM-AMI in patients with the angle between LAD and LCX of ＜ 79.43°is 3.6 times right than patients with the angle between 79.43°～ 108.73°.Between the survival group and the deceased group of AMI patients with left main lesion,there were no significant differences in the diameter and length of LM,the diameter of LAD and LCX,the angle between LM and LAD,the angle between LM and LCX and the angle between LAD and LCX (P＞0.05).Conclusions There was a correlation between the angle between LAD and LCX with the occurrence of LM-AMI in patients with left main lesion.The angle between LAD and LCX of ＜ 79.43° is the independent risk factor of LM-AMI in patients with left main lesion,but there was no correlation between the left coronary artery morphology and in-hospital mortality of patients with left main AMI.